3. Which medicinal products affect wound healing?

Some medicinal products, due to their mechanism of action, interact with some of the physiological factors involved in wound healing and may slow down the process. Such medicines include:

• cancer drugs which by altering the capacity for cell division and by their immunosuppressive properties, can slow down the healing process;

• systemic corticosteroid therapy which at high doses inhibits fibroblast proliferation, collagen synthesis and epithelialisation;

• immunosuppressants, non-steroidal anti-inflammatory drugs, which, due to their immunosuppressive properties, can also slow down the healing process.

Anticoagulants may alter the haemostasis phase of healing but do not cause delayed healing.

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